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|Hydrocortisone Enema

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Hydrocortisone Enema

Generic Name: Hydrocortisone Enema (hye-droe-KOR-ti-sone)
Brand Name: Colocort

Hydrocortisone Enema is used for:

Treating inflammatory conditions of the colon such as ulcerative colitis and ulcerative proctitis. It may also be used for other conditions as determined by your doctor.

Hydrocortisone Enema is a topical corticosteroid. It works by depressing the formation, release, and activity of different cells and chemicals that cause swelling, redness, and itching.

Do NOT use Hydrocortisone Enema if:

you are allergic to any ingredient in Hydrocortisone Enema
you are taking mifepristone
you have a rectal obstruction, abscess, or perforation; recent colostomy surgery; or a systemic fungal infection

Contact your doctor or health care provider right away if any of these apply to you.

Before using Hydrocortisone Enema:

Some medical conditions may interact with Hydrocortisone Enema. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a parasitic, bacterial, fungal, or viral infection; heart failure; diabetes; diarrhea; swelling of the esophagus; stomach problems; blockage of the bowel or other bowel problems; measles; tuberculosis; chickenpox; shingles; herpes infection of the eye; or you have received a recent vaccination
if you have a history of glaucoma, cataracts, or other eye problems; high blood pressure; weak bones; heart attack; ulcers; kidney problems; nerve problems (eg, myasthenia gravis); or a positive TB skin test

Some MEDICINES MAY INTERACT with Hydrocortisone Enema. Tell your health care provider if you are taking any other medicines, especially any of the following:

Barbiturates (eg, phenobarbital), carbamazepine, cholestyramine, colestipol, fluconazole, hydantoins (eg, phenytoin), lithium, rifampin, or thioamines (eg, propylthiouracil) because they may decrease Hydrocortisone Enema"s effectiveness
Aprepitant, clarithromycin, estrogens (eg, estradiol), macrolide immunosuppressants (eg, tacrolimus), nefazodone, or steroidal contraceptives (eg, birth control pills) because side effects such as adrenal gland or central nervous system problems may occur
Anticholinesterases (eg, pyridostigmine), anticoagulants (eg, warfarin), live vaccines, macrolide immunosuppressants (eg, tacrolimus), nondepolarizing muscle relaxants (eg, vecuronium), ritodrine, or theophylline because their actions and the risk of their side effects may be increased by Hydrocortisone Enema
Anticholinesterases (eg, pyridostigmine), anticoagulants (eg, warfarin), interleukin-2, mifepristone, or nondepolarizing muscle relaxants (eg, vecuronium) because their effectiveness may be decreased by Hydrocortisone Enema

This may not be a complete list of all interactions that may occur. Ask your health care provider if Hydrocortisone Enema may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Hydrocortisone Enema:

Use Hydrocortisone Enema as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with Hydrocortisone Enema. Talk to your pharmacist if you have questions about this information.
If you miss a dose of Hydrocortisone Enema and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use Hydrocortisone Enema.

Important safety information:

Do not use Hydrocortisone Enema for other rectal conditions at a later time.
Check with your doctor before having vaccinations while you are using Hydrocortisone Enema.
Hydrocortisone Enema should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Hydrocortisone Enema.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Hydrocortisone Enema while you are pregnant. It is not known if Hydrocortisone Enema is found in breast milk. If you are or will be breast-feeding while you use Hydrocortisone Enema, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Hydrocortisone Enema:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild irritation or dryness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); infection; rectal pain, burning, itching, bleeding, or irritation not present before using Hydrocortisone Enema.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Hydrocortisone Enema may be harmful if swallowed.

Proper storage of Hydrocortisone Enema:

Store Hydrocortisone Enema at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Hydrocortisone Enema out of the reach of children and away from pets.

General information:

If you have any questions about Hydrocortisone Enema, please talk with your doctor, pharmacist, or other health care provider.
Hydrocortisone Enema is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Hydrocortisone Enema. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006

Database Edition 06.4.1.002

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