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Some commonly used brand names are:
In the U.S.—
Memantine (me-MAN-teen) is used to treat moderate to severe Alzheimer"s disease. Memantine is not a cure for Alzheimer"s disease but it can help people with the disease. Memantine will not cure Alzheimer"s disease, and it will not stop the disease from getting worse.
This medicine is available only with your doctor"s prescription, in the following dosage forms:
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For memantine, the following should be considered:
Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to memantine. Also tell your doctor and pharmacist if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy—Memantine has not been studied in pregnant women. However, memantine has not been shown to cause birth defects or other problems in animal studies.
Breast-feeding—It is not known whether memantine passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely when breast feeding. Mothers who are taking this medicine and who wish to breast feed should discuss it with their doctor.
Children—Studies on this medicine have only been done in adult patients, and there is no specific information comparing the use of memantine in children with use in other age groups. This medicine is generally not used in children.
Older adults—This medicine has been studied in older adults and has not been shown to cause different side effects or problems in older people than it does in younger adults.
Other medical problems—The presence of other medical problems may affect the use of memantine. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This Medicine
Dosing—For patients taking the oral solution form of this medicine:
The dose of memantine will be different for different patients. Follow your doctor"s orders or the directions on the label . The following information includes only the average doses of memantine. If your dose is different, do not change it unless your doctor tells you to do so.
The number of tablets that you take depends on the strength of the medicine. Also, the number of doses you take each day and the time allowed between doses will be determined by your doctor.
Missed dose—If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage—To store this medicine:
Precautions While Using This Medicine
It is very important that your healthcare professional check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Bloating or swelling of face, arms, hands, lower legs, or feet; blurred vision; dizziness; headache; nervousness; pounding in the ears; rapid weight gain; slow or fast heartbeat; tingling of hands or feet; unusual weight gain or loss
Incidence not known
Abdominal pain; agitation; black, tarry stools; bleeding gums; blistering, peeling, loosening of skin; bloating; blood in urine or stools; chest pain; coma; constipation; continuing vomiting; convulsions; dark-colored urine; decreased urine output; depression; fainting; fast, pounding, or irregular heartbeat or pulse; general feeling of tiredness or weakness; high fever; high or low blood pressure; hostility; increased sweating; indigestion; infection from breathing foreign substances into the lungs; itching; lethargy; light-colored stools; lip smacking or puckering; loss of consciousness; muscle twitching; no blood pressure; no breathing; no pulse; numbness or tingling in face, arms, legs; pain or swelling in arms or legs without any injury; pain, tension, and weakness upon walking that subsides during periods of rest; pains in stomach, side, or abdomen, possibly radiating to the back; palpitations; pinpoint red spots on skin; pounding, slow heartbeat; puffing of cheeks; rapid or worm-like movements of tongue; rapid weight gain; recurrent fainting; red irritated eyes; red skin lesions, often with a purple center; seizures; severe constipation; severe headache; severe muscle stiffness; severe vomiting; sores, ulcers, or white spots in mouth or on lips; stomach pain; stupor; sudden severe weakness; swelling of face, ankles, or hands; total body jerking; trouble speaking or walking; troubled breathing; twitching, twisting, uncontrolled repetitive movements of tongue, lips, face, arms, or legs; uncontrolled chewing movements; uncontrolled movements of arms and legs; unusual bleeding or bruising; unusually pale skin; vomiting; yellow eyes and skin
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome.
Anxiety; back pain; bladder pain; bloody or cloudy urine; change in walking and balance; chills; clumsiness or unsteadiness; cough producing mucus; coughing; difficult, burning, or painful urination; difficulty breathing; difficulty moving; difficulty having a bowel movement (stool); diarrhea; discouragement; dry mouth; fear; feeling sad or empty; fever; frequent urge to urinate; general feeling of discomfort or illness; hyperventilation; insomnia; irregular heartbeats; irritability; joint pain; loss of appetite; loss of bladder control; loss of interest or pleasure; lower back or side pain; muscle pain or stiffness; nausea; nervousness; pain; pain in joints; restlessness; seeing, hearing, or feeling things that are not there; shortness of breath; sleepiness or unusual drowsiness; sore throat; tightness in chest; tiredness; trouble concentrating; trouble sleeping; unusual tiredness or weakness; vomiting; wheezing
Incidence not known
Burning feeling in chest or stomach; burning, numbness, pain, or tingling in all fingers except smallest finger; cold sweats; cool pale skin; decreased interest in sexual intercourse; difficulty swallowing; general feeling of discomfort or illness; heartburn; inability to have or keep an erection; increased hunger; large amount of fat in the blood; loss in sexual ability, desire, drive, or performance; nightmares; shakiness; slurred speech; stomach cramps; stomach upset; tenderness in stomach area; watery or bloody diarrhea
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
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