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|Doxorubicin Liposomal

Doxorubicin Liposomal

Doxorubicin Liposomal is used for:

Treating advanced ovarian cancer and AIDS-related Kaposi sarcoma in patients not affected by or intolerant to other chemotherapy therapies.

Doxorubicin Liposomal is an antineoplastic antibiotic. It works by killing cancer cells.

Do NOT use Doxorubicin Liposomal if:

• you are allergic to any ingredient in Doxorubicin Liposomal or to conventional doxorubicin
• you have bone marrow depression
• you are breast-feeding

Contact your doctor or health care provider right away if any of these apply to you.

Before using Doxorubicin Liposomal :

Some medical conditions may interact with Doxorubicin Liposomal . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant or planning to become pregnant
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have heart disease or liver problems
• if you have had radiation therapy
• if you have previously received treatment with other anticancer medicines (eg, daunorubicin, idarubicin, another anthracycline or anthracene)

Some MEDICINES MAY INTERACT with Doxorubicin Liposomal . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Barbiturates (eg, phenobarbital) or streptozocin because the effectiveness of Doxorubicin Liposomal may be decreased
• Calcium channel blockers (eg, verapamil), cyclophosphamide, cyclosporine, or paclitaxel because side effects, such as heart problems, may be increased
• Anticoagulants (eg, warfarin) or trastuzumab because the actions and side effects of these medicines may be increased
• Carbamazepine, digoxin, hydantoins (eg, phenytoin), live vaccines, or valproic acid because effectiveness may be decreased by Doxorubicin Liposomal

This may not be a complete list of all interactions that may occur. Ask your health care provider if Doxorubicin Liposomal may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Doxorubicin Liposomal :

Use Doxorubicin Liposomal as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Doxorubicin Liposomal is usually administered as an injection at your doctor"s office, hospital, or clinic. If you are using Doxorubicin Liposomal at home, carefully follow the injection procedures taught to you by your health care provider.
• If Doxorubicin Liposomal contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
• Drinking extra fluids while you are taking Doxorubicin Liposomal is recommended. Check with your doctor for instructions.
• If Doxorubicin Liposomal accidentally spills on your skin, wash it off immediately with soap and water.
• Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
• If you miss a dose of Doxorubicin Liposomal , contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Doxorubicin Liposomal .

Important safety information:

• Doxorubicin Liposomal may reduce the number of clot-forming cells (platelets) in your blood. To prevent bleeding, avoid situations in which bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark, tarry stools to your doctor.
• Doxorubicin Liposomal may lower your body"s ability to fight infection. Prevent infection by avoiding contact with people with colds or other infections. Notify your doctor of any signs of infection, including fever, sore throat, rash, or chills.
• Avoid vaccinations with live virus vaccines (eg, measles, mumps, oral polio) while you are taking Doxorubicin Liposomal . Vaccinations may be less effective.
• Doxorubicin Liposomal may cause the urine to turn red. This is harmless and usually goes away 1 to 2 days after receiving a dose of Doxorubicin Liposomal .
• LAB TESTS, including liver function, complete blood cell counts, and heart function, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
• Doxorubicin Liposomal is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.
• PREGNANCY and BREAST-FEEDING: Doxorubicin Liposomal has been shown to cause harm to the fetus. If you become pregnant, discuss with your doctor the benefits and risks of using Doxorubicin Liposomal during pregnancy. Doxorubicin Liposomal is excreted in breast milk. Do not breast-feed while taking Doxorubicin Liposomal .

Possible side effects of Doxorubicin Liposomal :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; hair loss; loss of appetite; nausea; pain, redness, or swelling at the injection site; red-colored urine 1 to 2 days after receiving Doxorubicin Liposomal ; tiredness; vomiting; weakness.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); back pain; bleeding or bruising; chest pain; cough; dizziness; fainting; flushing; hand-foot syndrome (tingling, burning, redness, swelling, flaking, small blisters or small sores on the palms of hands or sores of feet); headache; irregular or fast heartbeat; loose or bloody stools; rectal bleeding or irritation; serious infection (fever, chills, persistent sore throat); shortness of breath; sores in the mouth or on the lips; sudden weight gain; swelling of the face or ankles; tightness in the chest and throat; unusual tiredness.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include inflammation of the mouth.

Doxorubicin Liposomal is usually handled and stored by a health care provider. If you are using Doxorubicin Liposomal at home, store Doxorubicin Liposomal as directed by your pharmacist or health care provider. Keep Doxorubicin Liposomal out of the reach of children and away from pets.

General information:

• If you have any questions about Doxorubicin Liposomal , please talk with your doctor, pharmacist, or other health care provider.
• Doxorubicin Liposomal is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Doxorubicin Liposomal . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.