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|Dextroamphetamine ER Dextroamphetamine Mixed Salts |
Drugs search, click the first letter of a drug name: | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 1 | 2 | 3 | 4 | 5 | 6 | 8 | 9 Home Dextroamphetamine ERGeneric Name: dextroamphetamine sulfate Dosage Form: Extended-release capsules CII Rx only WarningAMPHETAMINES HAVE A HIGH POTENTIAL FOR ABUSE. ADMINISTRATION OF AMPHETAMINES FOR PROLONGED PERIODS OF TIME MAY LEAD TO DRUG DEPENDENCE AND MUST BE AVOIDED. PARTICULAR ATTENTION SHOULD BE PAID TO THE POSSIBILITY OF SUBJECTS OBTAINING AMPHETAMINES FOR NON-THERAPEUTIC USE OR DISTRIBUTION TO OTHERS, AND THE DRUGS SHOULD BE PRESCRIBED OR DISPENSED SPARINGLY. MISUSE OF AMPHETAMINES MAY CAUSE SUDDEN DEATH AND SERIOUS CARDIOVASCULAR ADVERSE EVENTS. Dextroamphetamine ER DescriptionDextroamphetamine sulfate is the dextro isomer of the compound d,l-amphetamine sulfate, a sympathomimetic amine of the amphetamine group. Chemically, dextroamphetamine is d-alpha-methylphenethylamine, and is present in all forms of dextroamphetamine sulfate extended-release capsules as the neutral sulfate. Structural Formula: Dextroamphetamine Sulfate Extended-Release CapsulesEach dextroamphetamine sulfate extended-release capsule is so prepared that an initial dose is released promptly and the remaining medication is released gradually over a prolonged period. Each capsule, with white opaque cap and white opaque body, contains dextroamphetamine sulfate. The 5 mg capsule is imprinted with an ® on the cap and is imprinted 8960 5 mg on the body in black. The 10 mg capsule is imprinted with an ® on the cap and is imprinted 8961 10 mg on the body in blue. The 15 mg capsule is imprinted with an ® on the cap and is imprinted 8962 15 mg on the body in pink. Inactive ingredients consist of Sugar Spheres NF, Titanium Dioxide USP, Gelatin NF, Shellac Glaze-45%, SD-45 Alcohol, Iron Oxide Black, Propylene Glycol USP, FD&C Blue #2/Indigo Carmine Lake, FD&C Red #40/Allura Red AC Lake, FD&C Blue #1/Brilliant Blue FCF Lake, D&C Yellow #10 Lake, SD3A Alcohol, Shellac NF, Dehydrated Alcohol USP, Isopropyl Alcohol USP, Butyl Alcohol NF, Strong Ammonia Solution NF, FD&C Blue #2 Aluminum Lake, D&C Red #7 Calcium Lake, Hydroxypropyl Methylcellulose USP/Hypromellose USP, Macrogol/Polyethylene Glycol NF, Purified Water USP, Ethylcellulose NF, Ammonium Hydroxide 28% NF, Medium Chain Triglycerides, Oleic Acid NF. Dextroamphetamine ER - Clinical PharmacologyAmphetamines are noncatecholamine, sympathomimetic amines with CNS stimulant activity. Peripheral actions include elevations of systolic and diastolic blood pressures and weak bronchodilator and respiratory stimulant action. There is neither specific evidence that clearly establishes the mechanism whereby amphetamines produce mental and behavioral effects in children, nor conclusive evidence regarding how these effects relate to the condition of the central nervous system. Dextroamphetamine sulfate extended-release capsules are formulated to release the active drug substance in vivo in a more gradual fashion than the standard formulation, as demonstrated by blood levels. The formulation has not been shown superior in effectiveness over the same dosage of the standard, noncontrolled-release formulations given in divided doses. PharmacokineticsThe pharmacokinetics of the tablet and sustained-release capsule were compared in 12 healthy subjects. The extent of bioavailability of the sustained-release capsule was similar compared to the immediate-release tablet. Following administration of three 5 mg tablets, average maximal dextroamphetamine plasma concentrations (Cmax) of 36.6 ng/mL were achieved at approximately 3 hours. Following administration of one 15 mg sustained-release capsule, maximal dextroamphetamine plasma concentrations were obtained approximately 8 hours after dosing. The average Cmax was 23.5 ng/mL. The average plasma T1/2 was similar for both the tablet and sustained-release capsule and was approximately 12 hours. In 12 healthy subjects, the rate and extent of dextroamphetamine absorption were similar following administration of the sustained-release capsule formulation in the fed (58 to 75 gm fat) and fasted state. Indications and Usage for Dextroamphetamine ERDextroamphetamine Sulfate Extended-Release Capsules are indicated in: NarcolepsyAttention Deficit Disorder with Hyperactivity - As an integral part of a total treatment program that typically includes other remedial measures (psychological, educational, social) for a stabilizing effect in pediatric patients (ages 3 years to 16 years) with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: Moderate to severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity. The diagnosis of this syndrome should not be made with finality when these symptoms are only of comparatively recent origin. Nonlocalizing (soft) neurological signs, learning disability, and abnormal EEG may or may not be present, and a diagnosis of central nervous system dysfunction may or may not be warranted. ContraindicationsAdvanced arteriosclerosis, symptomatic cardiovascular disease, moderate to severe hypertension, hyperthyroidism, known hypersensitivity or idiosyncrasy to the sympathomimetic amines, glaucoma. Agitated states. Patients with a history of drug abuse. During or within 14 days following the administration of monoamine oxidase inhibitors (hypertensive crises may result). WarningsSerious Cardiovascular EventsSudden Death in Patients with Pre-existing Structural Cardiac Abnormalities or Other Serious Heart ProblemsChildren and Adolescents – Sudden death has been reported in association with CNS stimulant treatment at usual doses in children and adolescents with structural cardiac abnormalities or other serious heart problems. Although some serious heart problems alone carry an increased risk of sudden death, stimulant products generally should not be used in children or adolescents with known serious structural cardiac abnormalities, cardiomyopathy, serious heart rhythm abnormalities, or other serious cardiac problems that may place them at increased vulnerability to the sympathomimetic effects of a stimulant drug. Adults – Sudden deaths, stroke, and myocardial infarction have been reported in adults taking stimulant drugs at usual doses for ADHD. Although the role of stimulants in these adult cases is also unknown, adults have a greater likelihood than children of having serious structural cardiac abnormalities, cardiomyopathy, serious heart rhythm abnormalities, coronary artery disease, or other serious cardiac problems. Adults with such abnormalities should also generally not be treated with stimulant drugs (see CONTRAINDICATIONS). Hypertension and Other Cardiovascular ConditionsStimulant medications cause a modest increase in average blood pressure (about 2 to 4 mmHg) and average heart rate (about 3 to 6 bpm), and individuals may have larger increases. While the mean changes alone would not be expected to have short-term consequences, all patients should be monitored for larger changes in heart rate and blood pressure. Caution is indicated in treating patients whose underlying medical conditions might be compromised by increases in blood pressure or heart rate, e.g., those with pre-existing hypertension, heart failure, recent myocardial infarction, or ventricular arrhythmia (see CONTRAINDICATIONS). Assessing Cardiovascular Status in Patients Being Treated with Stimulant MedicationsChildren, adolescents, or adults who are being considered for treatment with stimulant medications should have a careful history (including assessment for a family history of sudden death or ventricular arrhythmia) and physical exam to assess for the presence of cardiac disease, and should receive further cardiac evaluation if findings suggest such disease (e.g., electrocardiogram and echocardiogram). Patients who develop symptoms such as exertional chest pain, unexplained syncope, or other symptoms suggestive of cardiac disease during stimulant treatment should undergo a prompt cardiac evaluation. Psychiatric Adverse EventsPre-Existing Psychosis – Administration of stimulants may exacerbate symptoms of behavior disturbance and thought disorder in patients with a pre-existing psychotic disorder. Bipolar Illness – Particular care should be taken in using stimulants to treat ADHD in patients with comorbid bipolar disorder because of concern for possible induction of a mixed/manic episode in such patients. Prior to initiating treatment with a stimulant, patients with comorbid depressive symptoms should be adequately screened to determine if they are at risk for bipolar disorder; such screening should include a detailed psychiatric history, including a family history of suicide, bipolar disorder, and depression. Emergence of New Psychotic or Manic Symptoms – Treatment emergent psychotic or manic symptoms, e.g., hallucinations, delusional thinking, or mania in children and adolescents without a prior history of psychotic illness or mania can be caused by stimulants at usual doses. If such symptoms occur, consideration should be given to a possible causal role of the stimulant, and discontinuation of treatment may be appropriate. In a pooled analysis of multiple short-term, placebo-controlled studies, such symptoms occurred in about 0.1% (4 patients with events out of Aggression – Aggressive behavior or hostility is often observed in children and adolescents with ADHD, and has been reported in clinical trials and the postmarketing experience of some medications indicated for the treatment of ADHD. Although there is no systematic evidence that stimulants cause aggressive behavior or hostility, patients beginning treatment for ADHD should be monitored for the appearance of, or worsening of, aggressive behavior or hostility. Long-Term Suppression of GrowthCareful follow-up of weight and height in children ages 7 to 10 years who were randomized to either methylphenidate or non-medication treatment groups over 14 months, as well as in naturalistic subgroups of newly methylphenidate-treated and non-medication treated children over 36 months (to the ages of 10 to 13 years), suggests that consistently medicated children (i.e., treatment for 7 days per week throughout the year) have a temporary slowing in growth rate (on average, a total of about 2 cm less growth in height and 2.7 kg less growth in weight over 3 years), without evidence of growth rebound during this period of development. Published data are inadequate to determine whether chronic use of amphetamines may cause a similar suppression of growth, however, it is anticipated that they likely have this effect as well. Therefore, growth should be monitored during treatment with stimulants, and patients who are not growing or gaining height or weight as expected may need to have their treatment interrupted. SeizuresThere is some clinical evidence that stimulants may lower the convulsive threshold in patients with prior history of seizures, in patients with prior EEG abnormalities in absence of seizures, and, very rarely, in patients without a history of seizures and no prior EEG evidence of seizures. In the presence of seizures, the drug should be discontinued. Visual DisturbanceDifficulties with accommodation and blurring of vision have been reported with stimulant treatment. PrecautionsGeneral– The least amount feasible should be prescribed or dispensed at one time in order to minimize the possibility of overdosage. Information for Patients– Amphetamines may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or vehicles; the patient should therefore be cautioned accordingly. Drug InteractionsAcidifying agents– Gastrointestinal acidifying agents (guanethidine, reserpine, glutamic acid HCl, ascorbic acid, fruit juices, etc.) lower absorption of amphetamines. Urinary acidifying agents (ammonium chloride, sodium acid phosphate, etc.) increase the concentration of the ionized species of the amphetamine molecule, thereby increasing urinary excretion. Both groups of agents lower blood levels and efficacy of amphetamines. Adrenergic blockers– Adrenergic blockers are inhibited by amphetamines. Alkalinizing agents– Gastrointestinal alkalinizing agents (sodium bicarbonate, etc.) increase absorption of amphetamines. Urinary alkalinizing agents (acetazolamide, some thiazides) increase the concentration of the non-ionized species of the amphetamine molecule, thereby decreasing urinary excretion. Both groups of agents increase blood levels and therefore potentiate the actions of amphetamines. Antidepressants, tricyclic– Amphetamines may enhance the activity of tricyclic or sympathomimetic agents; d-amphetamine with desipramine or protriptyline and possibly other tricyclics cause striking and sustained increases in the concentration of d-amphetamine in the brain; cardiovascular effects can be potentiated. MAO inhibitors– MAOI antidepressants, as well as a metabolite of furazolidone, slow amphetamine metabolism. This slowing potentiates amphetamines, increasing their effect on the release of norepinephrine and other monoamines from adrenergic nerve endings; this can cause headaches and other signs of hypertensive crisis. A variety of neurological toxic effects and malignant hyperpyrexia can occur, sometimes with fatal results. Antihistamines– Amphetamines may counteract the sedative effect of antihistamines. Antihypertensives– Amphetamines may antagonize the hypotensive effects of antihypertensives. Chlorpromazine– Chlorpromazine blocks dopamine and norepinephrine reuptake, thus inhibiting the central stimulant effects of amphetamines, and can be used to treat amphetamine poisoning. Ethosuximide– Amphetamines may delay intestinal absorption of ethosuximide. Haloperidol– Haloperidol blocks dopamine and norepinephrine reuptake, thus inhibiting the central stimulant effects of amphetamines. Lithium carbonate– The stimulatory effects of amphetamines may be inhibited by lithium carbonate. Meperidine– Amphetamines potentiate the analgesic effect of meperidine. Methenamine therapy– Urinary excretion of amphetamines is increased, and efficacy is reduced, by acidifying agents used in methenamine therapy. Norepinephrine– Amphetamines enhance the adrenergic effect of norepinephrine. Phenobarbital– Amphetamines may delay intestinal absorption of phenobarbital; co-administration of phenobarbital may produce a synergistic anticonvulsant action. Phenytoin– Amphetamines may delay intestinal absorption of phenytoin; co-administration of phenytoin may produce a synergistic anticonvulsant action. Propoxyphene– In cases of propoxyphene overdosage, amphetamine CNS stimulation is potentiated and fatal convulsions can occur. Veratrum alkaloids– Amphetamines inhibit the hypotensive effect of veratrum alkaloids. Drug/Laboratory Test InteractionsAmphetamines can cause a significant elevation in plasma corticosteroid levels. This increase is greatest in the evening. Amphetamines may interfere with urinary steroid determinations. Carcinogenesis/Mutagenesis– Mutagenicity studies and long-term studies in animals to determine the carcinogenic potential of dextroamphetamine sulfate extended-release capsules have not been performed. PregnancyTeratogenic Effects. Pregnancy Category C - Dextroamphetamine sulfate extended-release capsules have been shown to have embryotoxic and teratogenic effects when administered to A/Jax mice and C57BL mice in doses approximately 41 times the maximum human dose. Embryotoxic effects were not seen in New Zealand white rabbits given the drug in doses 7 times the human dose nor in rats given 12.5 times the maximum human dose. While there are no adequate and well-controlled studies in pregnant women, there has been one report of severe congenital bony deformity, tracheoesophageal fistula, and anal atresia (VATER association) in a baby born to a woman who took dextroamphetamine sulfate with lovastatin during the first trimester of pregnancy. Dextroamphetamine sulfate extended-release capsules should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nonteratogenic Effects– Infants born to mothers dependent on amphetamines have an increased risk of premature delivery and low birth weight. Also, these infants may experience symptoms of withdrawal as demonstrated by dysphoria, including agitation, and significant lassitude. Nursing Mothers– Amphetamines are excreted in human milk. Mothers taking amphetamines should be advised to refrain from nursing. Pediatric Use– Long-term effects of amphetamines in pediatric patients have not been well established. Amphetamines are not recommended for use in pediatric patients under 3 years of age with Attention Deficit Disorder with Hyperactivity described under INDICATIONS AND USAGE. Clinical experience suggests that in psychotic children, administration of amphetamines may exacerbate symptoms of behavior disturbance and thought disorder. Amphetamines have been reported to exacerbate motor and phonic tics and Tourette"s syndrome. Therefore, clinical evaluation for tics and Tourette"s syndrome in children and their families should precede use of stimulant medications. Data are inadequate to determine whether chronic administration of amphetamines may be associated with growth inhibition; therefore, growth should be monitored during treatment. Drug treatment is not indicated in all cases of Attention Deficit Disorder with Hyperactivity and should be considered only in light of the complete history and evaluation of the child. The decision to prescribe amphetamines should depend on the physician"s assessment of the chronicity and severity of the child"s symptoms and their appropriateness for his or her age. Prescription should not depend solely on the presence of one or more of the behavioral characteristics. When these symptoms are associated with acute stress reactions, treatment with amphetamines is usually not indicated. Adverse ReactionsCardiovascular– Palpitations, tachycardia, elevation of blood pressure. There have been isolated reports of cardiomyopathy associated with chronic amphetamine use. Central Nervous System– Psychotic episodes at recommended doses (rare), overstimulation, restlessness, dizziness, insomnia, euphoria, dyskinesia, dysphoria, tremor, headache, exacerbation of motor and phonic tics and Tourette"s syndrome. Gastrointestinal– Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances. Anorexia and weight loss may occur as undesirable effects. Allergic– Urticaria. Endocrine– Impotence, changes in libido. Drug Abuse and DependenceDextroamphetamine sulfate is a Schedule II controlled substance. Amphetamines have been extensively abused. Tolerance, extreme psychological dependence and severe social disability have occurred. There are reports of patients who have increased the dosage to many times that recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with amphetamines include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. The most severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia. This is rare with oral amphetamines. OverdosageIndividual patient response to amphetamines varies widely. While toxic symptoms occasionally occur as an idiosyncrasy at doses as low as 2 mg, they are rare with doses of less than 15 mg; 30 mg can produce severe reactions, yet doses of 400 to 500 mg are not necessarily fatal. In rats, the oral LD50 of dextroamphetamine sulfate is 96.8 mg/kg. Manifestations of acute overdosage with amphetamines include restlessness, tremor, hyperreflexia, rhabdomyolysis, rapid respiration, hyperpyrexia, confusion, assaultiveness, hallucinations, panic states. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include arrhythmias, hypertension or hypotension and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea and abdominal cramps. Fatal poisoning is usually preceded by convulsions and coma. TreatmentConsult with a Certified Poison Control Center for up-to-date guidance and advice. Management of acute amphetamine intoxication is largely symptomatic and includes gastric lavage, administration of activated charcoal, administration of a cathartic, and sedation. Experience with hemodialysis or peritoneal dialysis is inadequate to permit recommendation in this regard. Acidification of the urine increases amphetamine excretion, but is believed to increase risk of acute renal failure if myoglobinuria is present. If acute, severe hypertension complicates amphetamine overdosage, administration of intravenous phentolamine (Bedford Laboratories) has been suggested. However, a gradual drop in blood pressure will usually result when sufficient sedation has been achieved. Chlorpromazine antagonizes the central stimulant effects of amphetamines and can be used to treat amphetamine intoxication. Since much of the dextroamphetamine sulfate extended-release capsule medication is coated for gradual release, therapy directed at reversing the effects of the ingested drug and at supporting the patient should be continued for as long as overdosage symptoms remain. Saline cathartics are useful for hastening the evacuation of pellets that have not already released medication. Dextroamphetamine ER Dosage and AdministrationAmphetamines should be administered at the lowest effective dosage and dosage should be individually adjusted. Late evening doses - particularly with the dextroamphetamine sulfate extended-release capsule form - should be avoided because of the resulting insomnia. Narcolepsy– Usual dose is 5 to 60 mg per day in divided doses, depending on the individual patient response. Narcolepsy seldom occurs in children under 12 years of age; however, when it does, dextroamphetamine sulfate extended-release capsules may be used. The suggested initial dose for patients aged 6 to 12 is 5 mg daily; daily dose may be raised in increments of 5 mg at weekly intervals until an optimal response is obtained. In patients 12 years of age and older, start with 10 mg daily; daily dosage may be raised in increments of 10 mg at weekly intervals until an optimal response is obtained. If bothersome adverse reactions appear (e.g., insomnia or anorexia), dosage should be reduced. Dextroamphetamine sulfate extended-release capsules may be used for once-a-day dosage wherever appropriate. Attention Deficit Disorder with Hyperactivity– Not recommended for pediatric patients under 3 years of age. In pediatric patients 6 years of age and older, start with 5 mg once or twice daily; daily dosage may be raised in increments of 5 mg at weekly intervals until optimal response is obtained. Only in rare cases will it be necessary to exceed a total of 40 mg per day. Dextroamphetamine sulfate extended-release capsules may be used for once-a-day dosage wherever appropriate. Where possible, drug administration should be interrupted occasionally to determine if there is a recurrence of behavioral symptoms sufficient to require continued therapy. How is Dextroamphetamine ER SuppliedDextroamphetamine Sulfate Extended-Release Capsules– Each capsule, with white opaque cap and white opaque body, contains dextroamphetamine sulfate. The 5 mg capsule is imprinted with an ® on the cap and is imprinted 8960 5 mg on the body in black. The 10 mg capsule is imprinted with an ® on the cap and is imprinted 8961 10 mg on the body in blue. The 15 mg capsule is imprinted with an ® on the cap and is imprinted 8962 15 mg on the body in pink. Available: 5 mg, 10 mg, and 15 mg in bottles of 100. Store at 20º to 25ºC (68º to 77ºF) [see USP Controlled Room Temperature]. Dispense in a tight, light-resistant container with a child-resistant closure. 5 mg 100"s:……………….NDC 0406-8960-01 10 mg 100"s:……………….NDC 0406-8961-01 15 mg 100"s:……………….NDC 0406-8962-01 Dextroamphetamine Sulfate Extended-Release Capsules are manufactured by Mallinckrodt Inc., Hobart, NY 13788. is a registered trademark of Mallinckrodt Inc. tyco Mallinckrodt Inc. MEDICATION GUIDEDextroamphetamine Sulfate Extended-Release Capsules Read the Medication Guide that comes with dextroamphetamine sulfate extended-release capsules before you or your child starts taking it and each time you get a refill. There may be new information. This Medication Guide does not take the place of talking to your doctor about your or your child"s treatment with dextroamphetamine sulfate extended-release capsules.
What are Dextroamphetamine Sulfate Extended-Release Capsules? Dextroamphetamine sulfate extended-release capsules are a central nervous system stimulant prescription medicine. It is used for the treatment of Attention-Deficit Hyperactivity Disorder (ADHD). Dextroamphetamine sulfate extended-release capsules may help increase attention and decrease impulsiveness and hyperactivity in patients with ADHD. Dextroamphetamine sulfate extended-release capsules should be used as a part of a total treatment program for ADHD that may include counseling or other therapies. Dextroamphetamine sulfate extended-release capsules are also used in the treatment of a sleep disorder called narcolepsy.
Who should not take Dextroamphetamine Sulfate Extended-Release Capsules? Dextroamphetamine sulfate extended-release capsules should not be taken if you or your child:
Dextroamphetamine sulfate extended-release capsules are not recommended for use in children less than 3 years old. Dextroamphetamine sulfate extended-release capsules may not be right for you or your child. Before starting dextroamphetamine sulfate extended-release capsules tell your or your child"s doctor about all health conditions (or a family history of) including:
Tell your doctor if you or your child is pregnant, planning to become pregnant, or breastfeeding. Can Dextroamphetamine Sulfate Extended-Release Capsules be taken with other medicines? Tell your doctor about all of the medicines that you or your child take including prescription and nonprescription medicines, vitamins, and herbal supplements. Dextroamphetamine sulfate extended-release capsules and some medicines may interact with each other and cause serious side effects. Sometimes the doses of other medicines will need to be adjusted while taking dextroamphetamine sulfate extended-release capsules. Your doctor will decide whether dextroamphetamine sulfate extended-release capsules can be taken with other medicines. Especially tell your doctor if you or your child takes:
Know the medicines that you or your child takes. Keep a list of your medicines with you to show your doctor and pharmacist. Do not start any new medicine while taking dextroamphetamine sulfate extended-release capsules without talking to your doctor first. How should Dextroamphetamine Sulfate Extended-Release Capsules be taken?
What are possible side effects of Dextroamphetamine Sulfate Extended-Release Capsules? See “ What is the most important information I should know about Dextroamphetamine Sulfate Extended-Release Capsules?” for information on reported heart and mental problems. Other serious side effects include:
Common side effects include:
Dextroamphetamine sulfate extended-release capsules may affect you or your child"s ability to drive or do other dangerous activities. Talk to your doctor if you or your child has side effects that are bothersome or do not go away. This is not a complete list of possible side effects. Ask your doctor or pharmacist for more information. How should I store Dextroamphetamine Sulfate Extended-Release Capsules?
General information about Dextroamphetamine Sulfate Extended-Release Capsules Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use dextroamphetamine sulfate extended-release capsules for a condition for which it was not prescribed. Do not give dextroamphetamine sulfate extended-release capsules to other people, even if they have the same condition. It may harm them and it is against the law. This Medication Guide summarizes the most important information about dextroamphetamine sulfate extended-release capsules. If you would like more information, talk with your doctor. You can ask your doctor or pharmacist for information about dextroamphetamine sulfate extended-release capsules that was written for healthcare professionals, or you can visit www.Mallinckrodt.com or call 1-888-744-1414, option 2, then 1 between the hours of 7am and 5pm CST. What are the ingredients in Dextroamphetamine Sulfate Extended-Release Capsules? Active Ingredient: dextroamphetamine sulfate Inactive Ingredients: Sugar Spheres NF, Titanium Dioxide USP, Gelatin NF, Shellac Glaze-45%, SD-45 Alcohol, Iron Oxide Black, Propylene Glycol USP, FD&C Blue #2/Indigo Carmine Lake, FD&C Red #40/Allura Red AC Lake, FD&C Blue #1/Brilliant Blue FCF Lake, D&C Yellow #10 Lake, SD3A Alcohol, Shellac NF, Dehydrated Alcohol USP, Isopropyl Alcohol USP, Butyl Alcohol NF, Strong Ammonia Solution NF, FD&C Blue #2 Aluminum Lake, D&C Red #7 Calcium Lake, Hydroxypropyl Methylcellulose USP/Hypromellose USP, Macrogol/Polyethylene Glycol NF, Purified Water USP, Ethylcellulose NF, Ammonium Hydroxide 28% NF, Medium Chain Triglycerides, Oleic Acid NF. This Medication Guide has been approved by the U.S. Food and Drug Administration. Mallinckrodt Inc. Rev 022707
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dextroamphetamine er dextroamphstamine mixed salts, dextroamphetamine er dextroamphdtamine mixed salts, dextroamphetamine er dextroamphrtamine mixed salts, dextroamphetamine er dextroamph4tamine mixed salts, dextroamphetamine er dextroamph3tamine mixed salts, dextroamphetamine er dextroampheramine mixed salts, dextroamphetamine er dextroamphefamine mixed salts, dextroamphetamine er dextroamphegamine mixed salts, dextroamphetamine er dextroampheyamine mixed salts, dextroamphetamine er dextroamphe6amine mixed salts, dextroamphetamine er dextroamphe5amine mixed salts, dextroamphetamine er dextroamphetzmine mixed salts, dextroamphetamine er dextroamphetsmine mixed salts, dextroamphetamine er dextroamphetwmine mixed salts, dextroamphetamine er dextroamphetqmine mixed salts, dextroamphetamine er dextroamphetanine mixed salts, dextroamphetamine er dextroamphetakine mixed salts, dextroamphetamine er dextroamphetajine mixed salts, dextroamphetamine er dextroamphetamune mixed salts, dextroamphetamine er dextroamphetamjne mixed salts, dextroamphetamine er dextroamphetamkne mixed salts, dextroamphetamine er dextroamphetamone mixed salts, dextroamphetamine er dextroamphetam9ne mixed salts, dextroamphetamine er dextroamphetam8ne mixed salts, dextroamphetamine er dextroamphetamibe mixed salts, dextroamphetamine er dextroamphetamime mixed salts, dextroamphetamine er dextroamphetamije mixed salts, dextroamphetamine er dextroamphetamihe mixed salts, dextroamphetamine er dextroamphetaminw mixed salts, dextroamphetamine er dextroamphetamins mixed salts, dextroamphetamine er dextroamphetamind mixed salts, dextroamphetamine er dextroamphetaminr mixed salts, dextroamphetamine er dextroamphetamin4 mixed salts, dextroamphetamine er dextroamphetamin3 mixed salts, dextroamphetamine er dextroamphetamine nixed salts, dextroamphetamine er dextroamphetamine kixed salts, dextroamphetamine er dextroamphetamine jixed salts, dextroamphetamine er dextroamphetamine muxed salts, dextroamphetamine er dextroamphetamine mjxed salts, dextroamphetamine er dextroamphetamine mkxed salts, dextroamphetamine er dextroamphetamine moxed salts, dextroamphetamine er dextroamphetamine m9xed salts, dextroamphetamine er dextroamphetamine m8xed salts, dextroamphetamine er dextroamphetamine mized salts, dextroamphetamine er dextroamphetamine miced salts, dextroamphetamine er dextroamphetamine mided salts, dextroamphetamine er dextroamphetamine mised salts, dextroamphetamine er dextroamphetamine mixwd salts, dextroamphetamine er dextroamphetamine mixsd salts, dextroamphetamine er dextroamphetamine mixdd salts, dextroamphetamine er dextroamphetamine mixrd salts, dextroamphetamine er dextroamphetamine mix4d salts, dextroamphetamine er dextroamphetamine mix3d salts, dextroamphetamine er dextroamphetamine mixes salts, dextroamphetamine er dextroamphetamine mixex salts, dextroamphetamine er dextroamphetamine mixec salts, dextroamphetamine er dextroamphetamine mixef salts, dextroamphetamine er dextroamphetamine mixer salts, dextroamphetamine er dextroamphetamine mixee salts, dextroamphetamine er dextroamphetamine mixed aalts, dextroamphetamine er dextroamphetamine mixed zalts, dextroamphetamine er dextroamphetamine mixed xalts, dextroamphetamine er dextroamphetamine mixed dalts, dextroamphetamine er dextroamphetamine mixed ealts, dextroamphetamine er dextroamphetamine mixed walts, dextroamphetamine er dextroamphetamine mixed szlts, dextroamphetamine er dextroamphetamine mixed sslts, dextroamphetamine er dextroamphetamine mixed swlts, dextroamphetamine er dextroamphetamine mixed sqlts, dextroamphetamine er dextroamphetamine mixed sakts, dextroamphetamine er dextroamphetamine mixed sapts, dextroamphetamine er dextroamphetamine mixed saots, dextroamphetamine er dextroamphetamine mixed salrs, dextroamphetamine er dextroamphetamine mixed salfs, dextroamphetamine er dextroamphetamine mixed salgs, dextroamphetamine er dextroamphetamine mixed salys, dextroamphetamine er dextroamphetamine mixed sal6s, dextroamphetamine er dextroamphetamine mixed sal5s, dextroamphetamine er dextroamphetamine mixed salta, dextroamphetamine er dextroamphetamine mixed saltz, dextroamphetamine er dextroamphetamine mixed saltx, dextroamphetamine er dextroamphetamine mixed saltd, dextroamphetamine er dextroamphetamine mixed salte, dextroamphetamine er dextroamphetamine mixed saltw, extroamphetamine er dextroamphetamine mixed salts, dxtroamphetamine er dextroamphetamine mixed salts, detroamphetamine er dextroamphetamine mixed salts, dexroamphetamine er dextroamphetamine mixed salts, dextoamphetamine er dextroamphetamine mixed salts, dextramphetamine er dextroamphetamine mixed salts, dextromphetamine er dextroamphetamine mixed salts, dextroaphetamine er dextroamphetamine mixed salts, dextroamhetamine er dextroamphetamine mixed salts, dextroampetamine er dextroamphetamine mixed salts, dextroamphtamine er dextroamphetamine mixed salts, dextroampheamine er dextroamphetamine mixed salts, dextroamphetmine er dextroamphetamine mixed salts, dextroamphetaine er dextroamphetamine mixed salts, dextroamphetamne er dextroamphetamine mixed salts, dextroamphetamie er dextroamphetamine mixed salts, dextroamphetamin er dextroamphetamine mixed salts, dextroamphetamineer dextroamphetamine mixed salts, dextroamphetamine r dextroamphetamine mixed salts, dextroamphetamine e dextroamphetamine mixed salts, dextroamphetamine er dextroamphetamine mixed salts, dextroamphetamine er dextroamphetamine mixed salts, dextroamphetamine er extroamphetamine mixed salts, dextroamphetamine er dxtroamphetamine mixed salts, dextroamphetamine er detroamphetamine mixed salts, dextroamphetamine er dexroamphetamine mixed salts, dextroamphetamine er dextoamphetamine mixed salts, dextroamphetamine er dextramphetamine mixed salts, dextroamphetamine er dextromphetamine mixed salts, dextroamphetamine er dextroaphetamine mixed salts, dextroamphetamine er dextroamhetamine mixed salts, dextroamphetamine er dextroampetamine mixed salts, dextroamphetamine er dextroamphtamine mixed salts, dextroamphetamine er dextroampheamine mixed salts, dextroamphetamine er dextroamphetmine mixed salts, dextroamphetamine er dextroamphetaine mixed salts, dextroamphetamine er dextroamphetamne mixed salts, dextroamphetamine er dextroamphetamie mixed salts, dextroamphetamine er dextroamphetamin mixed salts, dextroamphetamine er dextroamphetaminemixed salts, dextroamphetamine er dextroamphetamine ixed salts, dextroamphetamine er dextroamphetamine mxed salts, dextroamphetamine er dextroamphetamine mied salts, dextroamphetamine er dextroamphetamine mixd salts, dextroamphetamine er dextroamphetamine mixe salts, dextroamphetamine er dextroamphetamine mixedsalts, dextroamphetamine er dextroamphetamine mixed alts, dextroamphetamine er dextroamphetamine mixed slts, dextroamphetamine er dextroamphetamine mixed sats, dextroamphetamine er dextroamphetamine mixed sals, dextroamphetamine er dextroamphetamine mixed salt, edxtroamphetamine er dextroamphetamine mixed salts, dxetroamphetamine er dextroamphetamine mixed salts, detxroamphetamine er dextroamphetamine mixed salts, dexrtoamphetamine er dextroamphetamine mixed salts, dextoramphetamine er dextroamphetamine mixed salts, dextraomphetamine er dextroamphetamine mixed salts, dextromaphetamine er dextroamphetamine mixed salts, dextroapmhetamine er dextroamphetamine mixed salts, dextroamhpetamine er dextroamphetamine mixed salts, dextroampehtamine er dextroamphetamine mixed salts, dextroamphteamine er dextroamphetamine mixed salts, dextroampheatmine er dextroamphetamine mixed salts, dextroamphetmaine er dextroamphetamine mixed salts, dextroamphetaimne er dextroamphetamine mixed salts, dextroamphetamnie er dextroamphetamine mixed salts, dextroamphetamien er dextroamphetamine mixed salts, dextroamphetamin eer dextroamphetamine mixed salts, dextroamphetaminee r dextroamphetamine mixed salts, dextroamphetamine re dextroamphetamine mixed salts, dextroamphetamine e r dextroamphetamine mixed salts, dextroamphetamine er dextroamphetamine mixed salts, dextroamphetamine er d extroamphetamine mixed salts, dextroamphetamine er edxtroamphetamine mixed salts, dextroamphetamine er dxetroamphetamine mixed salts, dextroamphetamine er detxroamphetamine mixed salts, dextroamphetamine er dexrtoamphetamine mixed salts, dextroamphetamine er dextoramphetamine mixed salts, dextroamphetamine er dextraomphetamine mixed salts, dextroamphetamine er dextromaphetamine mixed salts, dextroamphetamine er dextroapmhetamine mixed salts, dextroamphetamine er dextroamhpetamine mixed salts, dextroamphetamine er dextroampehtamine mixed salts, dextroamphetamine er dextroamphteamine mixed salts, dextroamphetamine er dextroampheatmine mixed salts, dextroamphetamine er dextroamphetmaine mixed salts, dextroamphetamine er dextroamphetaimne mixed salts, dextroamphetamine er dextroamphetamnie mixed salts, dextroamphetamine er dextroamphetamien mixed salts, dextroamphetamine er dextroamphetamin emixed salts, dextroamphetamine er dextroamphetaminem ixed salts, dextroamphetamine er dextroamphetamine imxed salts, dextroamphetamine er dextroamphetamine mxied salts, dextroamphetamine er dextroamphetamine miexd salts, dextroamphetamine er dextroamphetamine mixde salts, dextroamphetamine er dextroamphetamine mixe dsalts, dextroamphetamine er dextroamphetamine mixeds alts, dextroamphetamine er dextroamphetamine mixed aslts, dextroamphetamine er dextroamphetamine mixed slats, dextroamphetamine er dextroamphetamine mixed satls, dextroamphetamine er dextroamphetamine mixed salst, ddextroamphetamine er dextroamphetamine mixed salts, deextroamphetamine er dextroamphetamine mixed salts, dexxtroamphetamine er dextroamphetamine mixed salts, dexttroamphetamine er dextroamphetamine mixed salts, dextrroamphetamine er dextroamphetamine mixed salts, dextrooamphetamine er dextroamphetamine mixed salts, dextroaamphetamine er dextroamphetamine mixed salts, dextroammphetamine er dextroamphetamine mixed salts, dextroampphetamine er dextroamphetamine mixed salts, dextroamphhetamine er dextroamphetamine mixed salts, dextroampheetamine er dextroamphetamine mixed salts, dextroamphettamine er dextroamphetamine mixed salts, dextroamphetaamine er dextroamphetamine mixed salts, dextroamphetammine er dextroamphetamine mixed salts, dextroamphetamiine er dextroamphetamine mixed salts, dextroamphetaminne er dextroamphetamine mixed salts, dextroamphetaminee er dextroamphetamine mixed salts, dextroamphetamine er dextroamphetamine mixed salts, dextroamphetamine eer dextroamphetamine mixed salts, dextroamphetamine err dextroamphetamine mixed salts, dextroamphetamine er dextroamphetamine mixed salts, dextroamphetamine er dextroamphetamine mixed salts, dextroamphetamine er ddextroamphetamine mixed salts, dextroamphetamine er deextroamphetamine mixed salts, dextroamphetamine er dexxtroamphetamine mixed salts, dextroamphetamine er dexttroamphetamine mixed salts, dextroamphetamine er dextrroamphetamine mixed salts, dextroamphetamine er dextrooamphetamine mixed salts, dextroamphetamine er dextroaamphetamine mixed salts, dextroamphetamine er dextroammphetamine mixed salts, dextroamphetamine er dextroampphetamine mixed salts, dextroamphetamine er dextroamphhetamine mixed salts, dextroamphetamine er dextroampheetamine mixed salts, dextroamphetamine er dextroamphettamine mixed salts, dextroamphetamine er dextroamphetaamine mixed salts, dextroamphetamine er dextroamphetammine mixed salts, dextroamphetamine er dextroamphetamiine mixed salts, dextroamphetamine er dextroamphetaminne mixed salts, dextroamphetamine er dextroamphetaminee mixed salts, dextroamphetamine er dextroamphetamine mixed salts, dextroamphetamine er dextroamphetamine mmixed salts, dextroamphetamine er dextroamphetamine miixed salts, dextroamphetamine er dextroamphetamine mixxed salts, dextroamphetamine er dextroamphetamine mixeed salts, dextroamphetamine er dextroamphetamine mixedd salts, dextroamphetamine er dextroamphetamine mixed salts, dextroamphetamine er dextroamphetamine mixed ssalts, dextroamphetamine er dextroamphetamine mixed saalts, dextroamphetamine er dextroamphetamine mixed sallts, dextroamphetamine er dextroamphetamine mixed saltts, dextroamphetamine er dextroamphetamine mixed saltss, etc.
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