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|Deferoxamine

Deferoxamine

Deferoxamine is used for:

Treating acute iron poisoning and chronic iron overload caused by anemias that require frequent blood transfusions.

Deferoxamine is an iron-chelating agent. It works by binding to excess iron in the blood so that it can be removed by the kidneys and bowels.

Do NOT use Deferoxamine if:

• you are allergic to any ingredient in Deferoxamine
• you have severe kidney problems or you are unable to urinate

Contact your doctor or health care provider right away if any of these apply to you.

Before using Deferoxamine :

Some medical conditions may interact with Deferoxamine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have brain or kidney disease or heart failure
• if you take vitamin C

Some MEDICINES MAY INTERACT with Deferoxamine . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Prochlorperazine because loss of consciousness may occur
• Gallium-67 because its effectiveness may be decreased by Deferoxamine

This may not be a complete list of all interactions that may occur. Ask your health care provider if Deferoxamine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Deferoxamine :

Use Deferoxamine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Deferoxamine is usually administered as an injection at your doctor"s office, hospital, or clinic. If you are using Deferoxamine at home, carefully follow the injection procedures taught to you by your health care provider.
• If Deferoxamine contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
• If you miss a dose of Deferoxamine , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Deferoxamine .

Important safety information:

• Deferoxamine may cause dizziness or changes in vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Deferoxamine . Using Deferoxamine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
• Do not take large doses of vitamin C without first checking with your doctor.
• Deferoxamine may turn your urine a reddish color. This is harmless and not a cause for concern.
• Lab tests, including eye exams and hearing tests, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
• The weight and growth of CHILDREN receiving Deferoxamine should be monitored every 3 months.
• Use Deferoxamine with extreme caution in CHILDREN younger than 3 years of age. Safety and effectiveness in this age group have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Deferoxamine during pregnancy. It is unknown if Deferoxamine is excreted in breast milk. Do not breast-feed while taking Deferoxamine .

Possible side effects of Deferoxamine :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; leg cramps; nausea; stomach upset; vomiting.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in the amount of urine produced; decreased hearing; fainting; fast heartbeat; fever, chills, or sore throat; muscle or joint pain; numbness or tingling of the face, hands, feet, or skin; pain, burning, swelling, blistering, or redness at the injection site; ringing in the ears; seizures; severe dizziness; unusual bruising or bleeding; vision changes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include change in the amount of urine produced; coma; paleness; rapid heartbeat.

Deferoxamine is usually handled and stored by a health care provider. If you are using Deferoxamine at home, store Deferoxamine as directed by your pharmacist or health care provider. Keep Deferoxamine out of the reach of children and away from pets.

General information:

• If you have any questions about Deferoxamine , please talk with your doctor, pharmacist, or other health care provider.
• Deferoxamine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Deferoxamine . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.