Cortisporin Cream

|Cortisporin Cream

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Cortisporin Cream

Generic Name: Hydrocortisone/Neomycin/Polymyxin B Cream (hye-droe-KOR-ti-sone/nee-oh-MYE-sin/pol-i-MIX-in)
Brand Name: Cortisporin

Cortisporin Cream is used for:

Treating inflammation (swelling, warmth, redness, pain) due to certain skin conditions when an infection is present.

Cortisporin Cream is a combination of 2 antibiotics and a corticosteroid. The antibiotics work by slowing the growth of, or killing, sensitive bacteria. The corticosteroid reduces inflammation.

Do NOT use Cortisporin Cream if:

  • you are allergic to any ingredient in Cortisporin Cream, to other aminoglycosides (eg, tobramycin), or to other corticosteroids (eg, prednisone)
  • you have a viral infection of the skin (eg, herpes simplex, vaccinia, chickenpox, shingles), tuberculosis of the skin, or a fungal skin infection
  • you are using Cortisporin Cream on your ear and you have a perforated ear drum

Contact your doctor or health care provider right away if any of these apply to you.

Before using Cortisporin Cream:

Some medical conditions may interact with Cortisporin Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have any kind of skin infection, cuts, scrapes, or lessened blood flow to your skin
  • if you have had a recent vaccination; have measles or tuberculosis; or you have had a positive tuberculosis test

Some MEDICINES MAY INTERACT with Cortisporin Cream. Because little, if any, of Cortisporin Cream is absorbed into the blood, the risk of it interacting with another medicine is low.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Cortisporin Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Cortisporin Cream:

Use Cortisporin Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Cortisporin Cream is for topical use only. Do not get Cortisporin Cream in your eyes. If you get Cortisporin Cream in your eyes, rinse immediately with cool tap water.
  • Wash your hands thoroughly before and after using Cortisporin Cream.
  • Apply a small amount of medicine to the affected area. Rub in gently.
  • To clear up your infection completely, continue using Cortisporin Cream for the full course of treatment even if you feel better in a few days.
  • If you miss a dose of Cortisporin Cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Cortisporin Cream.

Important safety information:

  • Cortisporin Cream is effective only against bacteria. It is not useful against fungal or viral infections.
  • It is important to use Cortisporin Cream for the full course of treatment. Failure to do so may decrease the effectiveness of Cortisporin Cream and may increase the risk that the bacteria will no longer be sensitive to Cortisporin Cream and will not be able to be treated by this or certain other antibiotics in the future.
  • Long-term or repeated use of Cortisporin Cream may cause a second infection. Your doctor may want to change your medicine to treat the second infection. Contact your doctor if signs of a second infection occur.
  • Do not exceed the recommended dose or use Cortisporin Cream for longer than prescribed without checking with your doctor.
  • Do not use Cortisporin Cream for other conditions at a later time.
  • Cortisporin Cream contains a corticosteroid. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains hydrocortisone or any other corticosteroid. If it does or you are uncertain, contact your doctor or pharmacist.
  • Check with your doctor before having any vaccinations while you are using Cortisporin Cream.
  • Use Cortisporin Cream with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
  • Corticosteroids may affect the growth rate in CHILDREN and adolescents in some instances. Your child"s growth may need to be checked regularly while using Cortisporin Cream.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Cortisporin Cream during pregnancy. It is unknown if Cortisporin Cream is excreted in breast milk after topical use. If you are or will be breast-feeding while you are using Cortisporin Cream, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Cortisporin Cream:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dryness; itching.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); acne-like rash; burning or peeling of the skin not present when you began using Cortisporin Cream; changes in hearing; decreased urination; excessive hair growth; inflamed hair follicles; inflammation around the mouth; loss of hearing; muscle weakness; increased or persistent pain, redness, irritation, or swelling; thinning, softening, or discoloration of the skin; unusual weight gain, especially in the face.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately. Symptoms may include increased thirst or urination; muscle weakness; unusual weight gain, especially in the face.

Proper storage of Cortisporin Cream:

Store Cortisporin Cream between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Keep the container tightly closed. Keep Cortisporin Cream out of the reach of children and away from pets.

General information:

  • If you have any questions about Cortisporin Cream, please talk with your doctor, pharmacist, or other health care provider.
  • Cortisporin Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Cortisporin Cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.

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