Clomiphene

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Clomiphene


Generic Name: Clomiphene (KLOE-mih-feen)
Brand Name: Clomid and Serophene

Clomiphene is used for:

Treating female infertility and forcertain conditions as determined by your doctor.

Clomiphene is an ovulatory stimulant. It works by helping to produce more hormones that cause your ovaries to release 1 or more eggs.

Do NOT use Clomiphene if:

  • you are allergic to any ingredient in Clomiphene
  • you are pregnant
  • you have abnormal vaginal bleeding
  • you have ovarian cysts (small growths on the ovaries) or enlargement not due to polycystic ovarian syndrome
  • you have or have ever had blockage of blood vessels (blood clots) in the legs, lungs, or other parts of the body
  • you have liver problems, uncontrolled thyroid or adrenal gland problems, or a brain lesion (eg, pituitary gland tumor)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Clomiphene :

Some medical conditions may interact with Clomiphene . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are planning to become pregnant or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have depression, endometriosis, polycystic ovarian syndrome, or uterine fibroids

Some MEDICINES MAY INTERACT with Clomiphene . However, no specific interactions with Clomiphene are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Clomiphene may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Clomiphene :

Use Clomiphene as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Clomiphene may be taken with or without food.
  • Properly timed sexual intercourse is important for good results. Ovulation usually occurs 5 to 10 days after a dose of Clomiphene .
  • If pregnancy has not been successful after 3 courses of treatment, further treatment is not recommended. Long-term use of Clomiphene is not recommended.
  • If you miss a dose of Clomiphene , contact your doctor for instructions.

Ask your health care provider any questions you may have about how to use Clomiphene .

Important safety information:

  • Clomiphene may cause dizziness, lightheadedness, or vision disturbances, including blurring, spots, and flashes. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Clomiphene . Using Clomiphene alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Enlargement of the ovaries may happen during or shortly after taking Clomiphene . Call your health care provider if you experience any stomach or pelvic pain, weight gain, pain, or stomach enlargement or discomfort while taking Clomiphene .
  • LAB TESTS, including pregnancy tests, will be needed while you are taking Clomiphene . Be sure to keep all doctor and lab appointments.
  • Use Clomiphene with caution in the ELDERLY because they may be more sensitive to its effects.
  • Clomiphene is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.
  • Pregnancy with more than 1 fetus (eg, twins) is possible while you are taking Clomiphene . Be sure you have discussed the potential complications and hazards of multiple pregnancy.
  • PREGNANCY and BREAST-FEEDING: Do not use Clomiphene if you are or become pregnant. If you suspect that you could be pregnant, contact your doctor; it is important to not take Clomiphene while pregnant. It is unknown if Clomiphene is excreted in breast milk. Do not breast-feed while taking Clomiphene .

Possible side effects of Clomiphene :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision or vision problems (spots or flashes); breast tenderness; dizziness; enlarged breasts; enlargement of the ovaries; flushing; headache; hot flashes; lightheadedness; mood change; nausea; pelvic pain or bloating; stomach pain; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)increased risk of cancer of the ovaries; over stimulation of the ovaries; spontaneous abortion.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include blurred vision; flushing; nausea; stomach pain; vomiting.

Proper storage of Clomiphene :

Store Clomiphene at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Clomiphene out of the reach of children and away from pets.

General information:

  • If you have any questions about Clomiphene , please talk with your doctor, pharmacist, or other health care provider.
  • Clomiphene is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Clomiphene . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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