Clindamycin Solution

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|Clindamycin Solution

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Clindamycin Solution


Generic Name: Clindamycin Injection Solution (klin-da-MYE-sin)
Brand Name: Cleocin

Infrequently, there are severe, rarely fatal, intestinal problems that can occur after use of Clindamycin Solution. Consult your doctor immediately if you develop persistent diarrhea, stomach pain, or blood or mucus in your stool. These symptoms may occur weeks after stopping use of Clindamycin Solution. Do not use anti-diarrhea products or narcotic pain medicines if you have these symptoms. These products may make the symptoms worse. Your doctor will monitor you closely while you are using Clindamycin Solution.


Clindamycin Solution is used for:

Treating serious infections caused by certain bacteria.

Clindamycin Solution is a lincomycin antibiotic. It works by stopping the production of essential proteins needed by certain bacteria to survive.

Do NOT use Clindamycin Solution if:

  • you are allergic to any ingredient in Clindamycin Solution or to lincomycin
  • you have meningitis, Crohn disease, antibiotic-associated colitis, or ulcerative colitis

Contact your doctor or health care provider right away if any of these apply to you.

Before using Clindamycin Solution:

Some medical conditions may interact with Clindamycin Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diarrhea, an intestinal disease, or liver disease
  • if you have a decreased or lack of allergic response

Some MEDICINES MAY INTERACT with Clindamycin Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Nondepolarizing muscle relaxants (eg, vecuronium) or succinylcholine because the actions and side effects of these medicines may be increased
  • Erythromycin because the effectiveness of Clindamycin Solution may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Clindamycin Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Clindamycin Solution:

Use Clindamycin Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Clindamycin Solution is usually administered as an injection at your doctor"s office, hospital, or clinic. If you are using Clindamycin Solution at home, carefully follow the injection procedures taught to you by your health care provider.
  • If the medicine contains particles, is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • Clindamycin Solution works best if it is taken at the same time each day.
  • To clear up your infection completely, continue using Clindamycin Solution for the full course of treatment even if you feel better in a few days.
  • Dispose of Clindamycin Solution, needles, syringes, and other materials properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when it is full.
  • If you miss a dose of Clindamycin Solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use Clindamycin Solution.

Important safety information:

  • If severe diarrhea, stomach pain/cramps, or bloody stools occur, contact your doctor at once. This could be a symptom of a serious side effect requiring immediate medical attention. Do not treat diarrhea without consulting with your doctor.
  • Clindamycin Solution is effective only against bacteria. It is not effective for treating viral infections (eg, the common cold).
  • It is important to use Clindamycin Solution for the full course of treatment. Failure to do so may decrease the effectiveness of this treatment and may increase the risk that the bacteria will no longer be sensitive to Clindamycin Solution and it will not be able to be treated by this or certain other antibiotics in the future.
  • Long-term or repeated use of Clindamycin Solution may cause a second infection. Your doctor may want to change your medicine to treat the second infection. Contact your doctor if signs of a second infection occur.
  • This medicine contains benzyl alcohol as a preservative. Benzyl alcohol has been associated with a fatal "gasping syndrome" in premature infants.
  • LAB TESTS, including liver function, kidney function, and complete blood cell counts, may be performed to monitor progress. Be sure to keep all doctor and lab appointments.
  • Use Clindamycin Solution with caution in the ELDERLY because they may be more sensitive to its effects, especially diarrhea. Monitor carefully for changes in bowel frequency.
  • When Clindamycin Solution is used in CHILDREN (16 years of age and younger), monitoring of organ system function is recommended.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Clindamycin Solution during pregnancy. Clindamycin Solution is excreted in breast milk. If you are or will be breast-feeding while you are using Clindamycin Solution, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Clindamycin Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; infrequent urination; nausea; pain or irritation at the injection site; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood or mucus in stools; difficulty swallowing; severe or continuing diarrhea; stomach pain/cramps; swelling of hands, eyes, or throat; yellowing of skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch&http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Clindamycin Solution:

Store Clindamycin Solution at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Keep Clindamycin Solution, along with needles and syringes, out of the reach of children and away from pets.

General information:

  • If you have any questions about Clindamycin Solution, please talk with your doctor, pharmacist, or other health care provider.
  • Clindamycin Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Clindamycin Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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