Clarithromycin Suspension

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Clarithromycin Suspension


Generic Name: Clarithromycin Oral Suspension (kla-RITH-roe-mye-sin)
Brand Name: Biaxin

Clarithromycin Suspension is used for:

Treating infections caused by certain bacteria.

Clarithromycin Suspension is a macrolide antibiotic. It works by stopping the growth of or killing sensitive bacteria by reducing the production of important proteins needed by the bacteria to survive.

Do NOT use Clarithromycin Suspension if:

  • you are allergic to any ingredient in Clarithromycin Suspension or any other macrolides (eg, erythromycin)
  • you are taking cisapride, cyclosporine, dofetilide, eletriptan, ergot alkaloids (eg, ergotamine, dihydroergotamine), H1 antagonists (eg, terfenadine, astemizole), pimozide, QT-prolonging agents (eg, quinidine, sotalol, thioridazine), quinolones (eg, ciprofloxacin), or sumatriptan

Contact your doctor or health care provider right away if any of these apply to you.

Before using Clarithromycin Suspension:

Some medical conditions may interact with Clarithromycin Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diarrhea, a stomach infection, a blood disorder, severe kidney problems, or liver problems

Some MEDICINES MAY INTERACT with Clarithromycin Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Rifampin because it may decrease Clarithromycin Suspension"s effectiveness
  • Dofetilide , macrolides and ketolides (eg, erythromycin, azithromycin), pimozide, QT-prolonging agents (eg, quinidine, sotalol, thioridazine), quinolones (eg, ciprofloxacin), or streptogramins (eg, mikamycin) because serious, possibly life-threatening side effects on the heart or irregular heartbeat may occur
  • Anticoagulants (eg, warfarin), aldosterone blockers (eg, spironolactone), benzodiazepines (eg, alprazolam), buspirone, carbamazepine, cilostazol, cisapride, colchicine, corticosteroids (eg, hydrocortisone), cyclosporine, digoxin, disopyramide, eletriptan, ergot alkaloids (eg, ergotamine, dihydroergotamine), H1 antagonists (eg, terfenadine, astemizole), HMG-CoA reductase inhibitors (eg, simvastatin), imatinib, macrolide immunosuppressants (eg, tacrolimus), macrolides and ketolides (eg, erythromycin, azithromycin), phosphodiesterase type-5 inhibitors (eg, sildenafil), rifampin, sumatriptan, theophyllines, or verapamil because the actions and side effects of these medicines may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Clarithromycin Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Clarithromycin Suspension:

Use Clarithromycin Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Clarithromycin Suspension by mouth with or without food.
  • Shake well before each use. Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • To completely rinse all of the medicine from your mouth, follow each dose with water or food.
  • Clarithromycin Suspension works best if it is taken at the same time each day.
  • To clear up your infection completely, take Clarithromycin Suspension for the full course of treatment. Keep taking it even if you feel better in a few days.
  • Do not miss any doses. If you miss a dose of Clarithromycin Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Clarithromycin Suspension.

Important safety information:

  • Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Be sure to use Clarithromycin Suspension for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Clarithromycin Suspension only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Long-term or repeated use of Clarithromycin Suspension may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Lab tests, such as complete blood counts, may be performed while you use Clarithromycin Suspension. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Clarithromycin Suspension should not be used in CHILDREN younger than 6 months old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Clarithromycin Suspension has been shown to cause harm to the fetus. Clarithromycin Suspension is not recommended for use during pregnancy except when no other antibiotics can be used. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Clarithromycin Suspension while you are pregnant. It is not known if Clarithromycin Suspension is found in breast milk. If you are or will be breast-feeding while you use Clarithromycin Suspension, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Clarithromycin Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal taste; diarrhea; headache; indigestion; nausea; stomach discomfort; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; confusion; decreased urination; depression; emotional or mood changes; hallucinations; nightmares; severe diarrhea; severe stomach pain/cramps; trouble sleeping.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include diarrhea; nausea; stomach pain; vomiting.

Proper storage of Clarithromycin Suspension:

Store Clarithromycin Suspension at room temperature between 68 and 77 degrees F (20 and 25 degrees C) in a well-closed container. Do not store in the refrigerator. Use within 14 days. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Clarithromycin Suspension out of the reach of children and away from pets.

General information:

  • If you have any questions about Clarithromycin Suspension, please talk with your doctor, pharmacist, or other health care provider.
  • Clarithromycin Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Clarithromycin Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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