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Baycol, |cerivastatin

cerivastatin

Generic Name: cerivastatin (seh RIH va stah tin)
Brand Names: Baycol

What is cerivastatin?

Cerivastatin was withdrawn from the U.S. market in 2001.

Cerivastatin blocks the production of cholesterol (a type of fat) in the body.

Cerivastatin is used to reduce the amounts of LDL (bad) cholesterol and total cholesterol in your blood. Cerivastatin also reduces the amounts of triglycerides (another type of fat) and apolipoprotein B (a protein needed to make cholesterol) in your blood and increases the amount of HDL (good) cholesterol in your blood. These actions are important in reducing the risk of hardening of the arteries, which can lead to heart attacks, stroke, and peripheral vascular disease.

Cerivastatin may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about cerivastatin?

Cerivastatin was withdrawn from the U.S. market in 2001.

Who should not take cerivastatin?

Before taking cerivastatin, tell your doctor if you

• drink alcoholic beverages,

• have kidney disease,

• have a chronic muscular disease, or

• have seizures or epilepsy.

You may not be able to take cerivastatin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

How should I take cerivastatin?

Take cerivastatin exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Eat a low-fat, low-cholesterol diet. To see beneficial effects from cerivastatin, avoid fatty, high-cholesterol foods. Follow your doctor"s directions.

Your doctor may want to monitor your liver function with blood tests before starting treatment with cerivastatin, at six and twelve weeks after both the start of your treatment and any increase in dose, and periodically (every 6 months) thereafter. Depending on the results of these tests, your doctor can determine how much monitoring you will require.

Grapefruit and grapefruit juice may interact with cerivastatin. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

Do not stop taking cerivastatin without first talking to your doctor. It may be weeks or months before beneficial effects from this medication are seen.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of cerivastatin.

What happens if I overdose?

Symptoms of an overdose of cerivastatin are not known.

What should I avoid while taking cerivastatin?

Grapefruit and grapefruit juice may interact with cerivastatin. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

Cerivastatin side effects

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

• muscle aches, pain, or weakness;

• a fever;

• "flu-like" symptoms;

• decreased urine or rust-colored urine;

• blurred vision; or

• yellowing of your skin or eyes.

Other, less serious side effects may be more likely to occur. Continue to take cerivastatin and talk to your doctor if you experience

• gas, bloating, nausea, stomach upset, heartburn, abdominal pain, constipation, or diarrhea;

• dizziness;

• headache; or

• a rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect cerivastatin?

• cyclosporine (Sandimmune, Neoral);

• gemfibrozil (Lopid), clofibrate (Atromid-S), or fenofibrate (Tricor);

• niacin (Nicolar, Nicobid, Slo-Niacin, others);

• erythromycin (E-Mycin, E.E.S., Ery-Tab, others) or clarithromycin (Biaxin); or

• itraconazole (Sporanox), fluconazole (Diflucan), or ketoconazole (Nizoral).

The medications listed above may interact with cerivastatin and damage your muscles. Generally, these medicines are not used together.

Drugs other than those listed here may also interact with cerivastatin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

• Your pharmacist has additional information about cerivastatin written for health professionals that you may read.

What does my medication look like?

Cerivastatin was withdrawn from the U.S. market in 2001.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.