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|Amiloride

Amiloride

Amiloride is used for:

Preventing development of low blood potassium or helping to restore normal blood potassium in patients with high blood pressure or heart failure. It is usually used with other medicines. It may also be used to treat other conditions as determined by your doctor.

Amiloride is a potassium-sparing diuretic. It works by making the kidneys eliminate sodium (salt) and water from the body while retaining potassium.

Do NOT use Amiloride if:

• you are allergic to any ingredient in Amiloride
• you are taking potassium supplements or potassium-sparing diuretics (eg, aldosterone, triamterene)
• you are unable to urinate
• you have high blood potassium levels or kidney problems due to diabetes or other severe kidney disease

Contact your doctor or health care provider right away if any of these apply to you.

Before using Amiloride :

Some medical conditions may interact with Amiloride . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have heart problems, diabetes, kidney damage caused by diabetes, liver or kidney problems, low blood sodium levels, or a high acidity of body fluids, or you are dehydrated

Some MEDICINES MAY INTERACT with Amiloride . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin II receptor antagonists (eg, valsartan), cyclosporine, otherpotassium-sparing diuretics (eg, aldosterone, triamterene) or potassium supplements because high blood potassium levels may occur and cause listlessness, confusion, abnormal skin sensations of the arms and legs, heaviness of the limbs, slow or irregular heartbeat, or stopping of the heart
• Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin) because the effectiveness of Amiloride may be decreased and the risk of kidney problems and high blood potassium levels may be increased
• Lithium or quinidine because risk of side effects and toxicity may be increased by Amiloride

This may not be a complete list of all interactions that may occur. Ask your health care provider if Amiloride may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Amiloride :

Use Amiloride as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Amiloride should be taken with food.
• When you first start taking Amiloride , it may cause an increase in urine or in frequency of urination. To prevent this from affecting sleep, try not to take any dose later than 6 pm.
• If you miss a dose of this medicine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Amiloride .

Important safety information:

• Amiloride may cause drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Amiloride . Using Amiloride alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Do not use a salt substitute or potassium supplement without checking with your doctor.
• LAB TESTS, including electrolyte concentration levels and monitoring blood pressure, may be performed to monitor your progress. Be sure to keep all doctor and lab appointments.
• Use Amiloride with caution in the ELDERLY because they may be more sensitive to its effects.
• Amiloride is not recommended for use in CHILDREN; safety and effectiveness have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Amiloride during pregnancy. It is unknown if Amiloride is excreted in breast milk. Do not breast-feed while taking Amiloride .

Possible side effects of Amiloride :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache; loss of appetite; nausea; weakness.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dry mouth; excessive thirst; slowed heart rate; unusual muscle weakness; unusual tiredness; vomiting.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include lightheadedness; nausea; vomiting; weakness.

Store Amiloride at room temperature between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Amiloride out of the reach of children and away from pets.

General information:

• If you have any questions about Amiloride , please talk with your doctor, pharmacist, or other health care provider.
• Amiloride is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Amiloride . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.